Enhancing the Photocatalytic Conversion of Pt(IV) Substrates by Flavoprotein Engineering
نویسندگان
چکیده
Our recent work demonstrates that certain flavoproteins can catalyze the redox activation of Pt(IV) prodrug complexes under light irradiation. Herein, we used site-directed mutagenesis on mini singlet oxygen generator (mSOG) to modulate photocatalytic activity this flavoprotein toward two model substrates. Among prepared mutants, Q103V mSOG displayed enhanced catalytic efficiency as a result its longer triplet excited-state lifetime. This study shows, for first time, protein engineering improve capacity metal-containing
منابع مشابه
control of the optical properties of nanoparticles by laser fields
در این پایان نامه، درهمتنیدگی بین یک سیستم نقطه کوانتومی دوگانه(مولکول نقطه کوانتومی) و میدان مورد مطالعه قرار گرفته است. از آنتروپی ون نیومن به عنوان ابزاری برای بررسی درهمتنیدگی بین اتم و میدان استفاده شده و تاثیر پارامترهای مختلف، نظیر تونل زنی(که توسط تغییر ولتاژ ایجاد می شود)، شدت میدان و نسبت دو گسیل خودبخودی بر رفتار درجه درهمتنیدگی سیستم بررسی شده اشت.با تغییر هر یک از این پارامترها، در...
15 صفحه اولstudy of cohesive devices in the textbook of english for the students of apsychology by rastegarpour
this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...
Enhancing the Photocatalytic Activity of Nano Nd-TiO2@SiO2 by coupled systems
Metal doped TiO2 catalysts were synthesized by sol-gel method and their activities were determined for degradation of methyl orang as a pollutant. Nd-doped TiO2 showed the maximum activity comparing with others. Colloidal SiO2 was used as a support to increase the surface area and also the activity. Nano-TiO2/SiO2/Nd was synthesized by sol-gel method and it was characterized using XRD, XRF, SEM...
متن کاملNitroalkanes as reductive substrates for flavoprotein oxidases.
Nitroalkanes have been found to be general reductive substrates for D-amino acid oxidase, glucose oxidase and L-amino acid oxidase. These enzymes show different specificities for the structure of the nitroalkane substrate. The stoichiometry of the D-amino acid oxidase reaction is straightforward, consisting of the production of one mole each of aldehyde, nitrite and hydrogen peroxide for each m...
متن کاملthe role of task-based techniques on the acquisition of english language structures by the intermediate efl students
this study examines the effetivenss of task-based activities in helping students learn english language structures for a better communication. initially, a michigan test was administered to the two groups of 52 students majoring in english at the allameh ghotb -e- ravandi university to ensure their homogeneity. the students scores on the grammar part of this test were also regarded as their pre...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Physical Chemistry Letters
سال: 2021
ISSN: ['1948-7185']
DOI: https://doi.org/10.1021/acs.jpclett.1c00802